Nattokinase
with COQ10, Bromelain, Turmeric, aged garlic extract & much more
What this formula does to the vessels?Choose your offer
90 day money back guarantee
Get it quick: fast shipping available to the United States
Clinicians' Choice
471 clinicians recommend this formula to their patients without compensation.
Dr. Margaret Chen, MD, FACC |Medical professionalI look for formulas that are transparent about potency. 10,000 FU stated on the label, plus CoQ10 and circulation-supporting botanicals, is a combination I feel comfortable discussing with patients.
Mechanism of action
What This Formula Actually Does
One enzyme, one job — and a supporting cast that helps it along.
Fibrin builds up
Fibrin is the web-like protein your body uses for repair. Over time it can accumulate in vessels and restrict blood flow.
Nattokinase clears it
Nattokinase is a fibrinolytic enzyme. Its measured job is simple: it breaks fibrin down, strand by strand.
Blood flows freely again
With less fibrin in the way, blood moves more easily — that's healthy circulation.
7 supporting ingredients
How the Rest of the Formula Supports Your Vessels
Nattokinase targets fibrin while each supporting ingredient plays a different role in circulation and vessel health.
10,000 FU
Clearly stated enzyme activity
Made in Japan
Authentic Japanese natto source
Batch Tested
Certificate of Analysis available
90 Days
Money-back guarantee
Buying Separately Costs a Fortune
Every ingredient in this formula is available on its own. Add up what they cost as standalone bottles, and the difference is hard to ignore.
Bought separately
- Nattokinase 10,000 FU$30on Amazon
- CoQ10$30on Amazon
- Bromelain$18on Amazon
- Turmeric extract$21on Amazon
- Aged garlic extract$30on Amazon
- Pine bark extract$19on Amazon
- Grape seed extract$18on Amazon
- Dandelion root$25on Amazon
Novelle — all 8 in one bottle
- All 8 ingredients in one daily serving
- 10,000 FU nattokinase, clearly stated
- Made in Japan, batch tested
- One bottle instead of eight
Separate-bottle prices reflect typical Amazon listings at comparable strengths.
A Formula Built to Work as One.
Nattokinase is the engine of this formula. But an engine runs best with the right systems around it — so every other ingredient exists to support the same outcome: healthy blood flow.
One core enzyme, at the studied level
10,000 FU of nattokinase per daily serving — the activity level used in the human research. This is the engine of the formula.
Seven supporting ingredients, one shared job
CoQ10, turmeric, aged garlic, bromelain, pine bark, grape seed and dandelion root are each chosen to back the enzyme's work: circulation, cellular energy, and antioxidant support.
Nothing rides along for the ride
Every ingredient has a defined role in the same system. No fillers, no fairy-dust doses, no ingredients that duplicate each other's job.
Don't Just Trust the Front of the Bottle.
- Country of manufacture: Made in Japan
- Batch testing: Enzyme activity is tested for each batch
- Certificate of Analysis: Available to view below
Why 10,000 FU?
FU measures fibrinolytic enzyme activity — not weight.
Human studies of nattokinase have used different doses, populations, and designs. Some findings have been encouraging; others have not shown meaningful benefit.
Novelle clearly states 10,000 FU per daily serving, so you know exactly the activity level you're buying.
Your 3-step protocol
Simple Daily Routine
1 bottle
60 vegetarian capsules
2 capsules daily
With water, any time of day
30 days
Each bottle lasts one month
What Should I Expect?
Not a stimulant
You shouldn't expect an immediate sensation after taking it.
Part of a longer-term routine
People use supplements like this as part of a longer-term cardiovascular wellness routine, not for an instant effect.
Responses vary
Individual responses vary from person to person.
That's one reason Novelle gives you 90 days to decide whether it's right for you — and why most customers start with a 3-bottle, 90-day supply.
90
Days
Try Novelle for 90 Days — Without Risking Your Purchase.
Take Novelle as directed. If you decide it isn't right for you within 90 days, contact us for a refund under our guarantee policy.
How does the guarantee work?People who decided not to wait.
Why customers added Novelle Nattokinase to their daily routine.
7,139 verified reviews
- 5 ★77%
- 4 ★17%
- 3 ★4%
- 2 ★1%
- 1 ★1%
Verified buyer reviews collected post-purchase. Reviews are matched to a real order before they are published.
I had to read my labs twice
“My fibrinogen was 420 last November — flagged high. Three months on Novelle it came back at 320, and my LDL dropped from 142 to 102. I honestly thought the lab mixed up my results. I put both reports side by side just to believe it.”
122/78. I almost cried.
“My home readings sat around 145 for two years. This morning the cuff said 122/78 and I made my husband check it with me because I didn't trust it. Ten weeks in and it's been in the low 120s all week.”
My cardiologist asked what I changed
“I get a carotid ultrasound every year because of family history. This year the tech said the wall looked better than my last scan, and my cardiologist actually asked what I was doing differently. Only thing new was two capsules every morning.”
Total cholesterol 152 — best in a decade
“I've been fighting my cholesterol since my fifties. Last panel: total 152, LDL 82. The doctor wrote 'results improved compared to previous testing' right on the report. I circled the numbers and stuck it on the fridge.”
Passed my stress test with room to spare
“Two years ago I had to stop the treadmill test early. This spring I went the full protocol, pressure stayed at 118/76, and the nurse joked I should slow down. I walked out of that clinic grinning like a kid.”
Clean ECG after years of worry
“Palpitations had me nervous for years. My latest ECG came back normal sinus rhythm, heart rate 72, and my doctor said everything looked steady. I didn't realize how much stress I'd been carrying until I read that line.”
More written reviews
12 of 7,139My morning readings finally moved
“My blood pressure had hovered in the mid-140s for years no matter what I tried. Around month three, my morning readings were sitting in the low 130s. My doctor asked what I had changed — two capsules with breakfast is the only answer I had.”
Cholesterol came down at my checkup
“At my spring panel my total cholesterol was 232. Six months on this and my new labs came back at 208, with LDL down almost 20 points. The only thing different in my routine was taking this every morning.”
My hands aren't cold anymore
“For years my hands and feet felt icy by evening, even in summer. Around week six it just stopped — my fingers stay warm now, and my husband noticed the change before I did.”
The pharmacy cuff reads lower
“I take a statin, so I cleared this with my doctor first. The blood pressure cuff at the pharmacy used to read 148 over 92 every visit. Last month it was 132 over 84. My doctor saw the numbers himself and told me to keep doing what I'm doing.”
Stairs don't wind me anymore
“The three flights to my office used to leave me catching my breath at the top. By the second bottle I was walking up them without thinking about it. My legs feel lighter all day.”
The heaviness in my legs is gone
“By the end of every day my calves felt heavy and tight. Two months in, that ache is basically gone — I'm on my feet gardening at six in the evening without noticing my legs at all.”
Questions Before You Start?
Safety first: Nattokinase may affect clotting. Speak with a healthcare professional before use if you take anticoagulants, antiplatelet medication or aspirin, have a bleeding disorder, are pregnant or nursing, or have upcoming surgery.
FU stands for Fibrinolytic Units — a measure of enzyme activity. Each 2-capsule daily serving provides 10,000 FU of nattokinase.
You've done the research. Now choose the supply that fits your routine.
- Made in Japan
- 10,000 FU
- Batch tested
- 90-day guarantee