Hormone + Metabolic Support
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2,000 mg myo-inositol — the dose used in clinical insulin research — helps your cells respond to insulin again instead of ignoring it.
When blood sugar stops spiking and dropping, the afternoon wall and the 'I need something sweet' urge fade.
High insulin tells the body to store fat around the middle. Lower the signal and the midsection finally responds to what you're already doing.
Insulin resistance pushes testosterone up after 40 — the driver behind jawline acne, chin hair and thinning at the part.
Stabilising insulin takes pressure off an already-shifting hormonal rhythm in your forties and fifties.
Blood-sugar swings feel like anxiety, brain fog and irritability. Flatten the curve and the day feels level.
These aren't six separate problems. They're one root cause — insulin resistance, which accelerates as estrogen declines after 40.
The hallmark sign of high insulin
Blood sugar spiking, then dropping
Insulin overshoot after meals
Insulin driving testosterone up
Glucose dysregulation
Insulin rises years before glucose does
Based on a 2,140-woman survey after 8 weeks of daily use.
Reported fewer sugar cravings & no 3pm crash
within 2 weeks
Said energy stayed level all day
by week 4
Noticed midsection weight finally moving
by week 8
Saw calmer skin & fewer androgen symptoms
by week 8
Most women over 40 are told their weight, cravings, skin and energy are separate problems. They're usually one problem: cells that have stopped responding to insulin — and a body that keeps making more of it.
After 40, falling estrogen makes cells less responsive to insulin. Your pancreas compensates by producing more of it — often for years before anything shows on a standard blood test.
High circulating insulin is a storage signal. It tells the body to hold fat — preferentially around the abdomen — and blocks it from being released, no matter how carefully you eat.
Excess insulin pushes the ovaries to produce more testosterone. That shows up as jawline acne, chin hair, thinning at the part and cycles that skip.
Glucose spikes, insulin overshoots, blood sugar drops. The 3pm wall, the shakiness, the sugar hunting at 9pm — and cortisol from each crash raises glucose again.
Insulin+ breaks the loop at its source — 2,000 mg myo-inositol restores the insulin signal inside the cell, magnesium supports glucose handling, rhodiola blunts the cortisol side, and SRI-81™ Shatavari steadies hormonal rhythm through perimenopause.
The insulin gold standard.
A secondary messenger inside the insulin signalling pathway. The 2 g daily serving matches the dose most widely used in clinical research on insulin resistance, fasting insulin and androgen excess in women.
If you read labels before you buy, this section is for you.
Each run is tested by an independent ISO-accredited lab for identity, potency, heavy metals and microbials before release.
Blended and packed in the USA in an FDA-registered, cGMP-compliant facility.
Every active is listed with its exact milligram dose. Proprietary blends hide underdosing — we list the numbers.
No added sugar, artificial colours, sucralose, fillers, soy, dairy or gluten. Vegan and non-GMO.
Swipe through the timeline women report back to us.
As myo-inositol starts supporting insulin signalling, the glucose rollercoaster flattens. The 3pm wall softens and the evening sugar hunt loses its grip.
No supplement reverses years of insulin resistance overnight. Here is the realistic sequence, based on the inositol literature and what customers report.
Glucose is the fastest-moving lever. Most women notice the afternoon crash softening and evening cravings quieting before anything visible changes.
With fewer spikes, circulating insulin comes down. Sleep deepens, post-meal bloating eases and the shaky pre-meal irritability fades.
Inositol research measures outcomes at 12 weeks for a reason. Lower insulin means stored abdominal fat becomes accessible and testosterone-driven symptoms ease.
Metabolic change is cumulative. Women who stay consistent past month three consistently report the largest difference at the waist and in the mirror.
This is why the guarantee runs a full 90 days — the timeline hormones actually work on. Read the 90-day guarantee.
"Women over 40 are handed a symptom list — weight, cravings, skin, energy — when the common thread is insulin. Insulin+ was built at the doses that pathway actually responds to."
What other clinicians say
"By 40, most of my patients have some degree of insulin resistance and no one has told them. Insulin+ uses myo-inositol at the level used in the trials — not fairy-dusted for a label claim."
Dr. Michelle Johnson, MD, FACOG
Board-certified OB/GYN · Atlanta, GA
"Insulin sensitivity is the lever most midlife protocols ignore. Fasting insulin rises years before glucose does, and inositol is one of the better-studied nutritional ways to support that pathway."
Dr. Meera Sethi, MD
Endocrinologist · Reproductive & metabolic health
"My clients actually drink this one. After 8–12 weeks they report no afternoon crash, far fewer cravings and movement at the waist — exactly what you'd expect from consistent inositol and magnesium intake."
Kate Donnelly, MS, RDN
Registered dietitian nutritionist
Clinicians are compensated for their time reviewing the formula. Statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
"I've eaten the same way for twenty years and after 45 the weight went straight to my middle and stayed there. My doctor said my labs were 'borderline'. Twelve weeks on this and I'm down two inches at the waist without changing anything else. The 3pm crash disappeared in the first fortnight."
"I used to hit 4pm and physically need sugar — then be starving again an hour later. That whole cycle has stopped. I'm not white-knuckling anything, the urge just isn't there. My energy is level from morning to evening for the first time in years."
"After 45 the weight gathered around my middle and the evening grazing felt impossible to stop. Four months later the cravings are quiet, the scale is finally moving and my fasting glucose came down at my last check-up. My GP asked what I'd changed."
"I've bought inositol in capsules twice and quit both times — six horse pills a day. This tastes like strawberry lemonade so I actually take it. Seven weeks in: no post-lunch slump, no shaky hungry feeling, and my hot flashes have softened too."
"Thinning at the temples, chin hair, and a stomach that appeared out of nowhere at 42. Nobody connected them until I read about insulin driving testosterone. My stylist can see new growth at the hairline, the brain fog has lifted and my waistbands fit again."
"I ran out on holiday and didn't reorder for two weeks. The afternoon crashes, the sugar hunting at 9pm and the bloat came straight back — almost on schedule. That was my proof it was doing something. I'm on the subscription now."
"The shaky, irritable, snappy feeling I'd been calling anxiety for three years mostly tracked with how long since I'd eaten. Since starting this it's flattened out. My teenager said 'you've been nicer'. I'm also sleeping through the night far more often."
"The energy rollercoaster was the hardest part — great at 10am, useless by 2pm. Ten weeks in I feel steady in a way I haven't in years, and I don't plan my day around when I'll crash anymore."
"I read labels for a living. 2,000 mg of myo-inositol is the amount actually used in the insulin studies — most products give you a fraction and hide it in a blend. Eight weeks in: no crashes on a twelve-hour shift, less bloat, better sleep, no jitters."
"I was forgetting words mid-sentence and blaming my age. It turns out my blood sugar was on a rollercoaster all day. Fourteen weeks in the clarity is back, the afternoon dip is barely there, and my midsection is slowly changing shape."
"I was waking at 2am hungry and hot most nights. Now it's maybe once a fortnight. Sleeping through has fixed things I never connected to blood sugar — my skin, my patience, the bloating after dinner."
"Irregular cycles, jawline breakouts and weight I couldn't shift — all pointing at insulin, which nobody had ever mentioned to me. I'm on my third consecutive cycle around 31–33 days, my skin is calmer and the cravings that ruled my evenings are gone."
“I spent eleven years being told my bloodwork was normal. Nobody ever measured my insulin. I built Insulin+ because women over 40 deserve the root cause, not another list of symptoms to live with.”
Jessica Ellison — Founder, Novelle
One stick pack into 8–16 oz of cold water. No chalk, no grit, no sugar.
Many women take it before their largest meal. Caffeine-free, so timing is yours.
Cravings and crashes go first. Waist, skin and cycles follow over 8–12 weeks.
Most 'hormone' supplements never touch insulin — the mechanism behind most of what changed after 40.
| Insulin+ | Typical hormone pill | Multivitamin | |
|---|---|---|---|
| 2,000 mg myo-inositol (clinical insulin dose) | |||
| Targets insulin resistance at the source | |||
| Supports blood sugar & craving control | |||
| Addresses insulin-driven androgen symptoms | |||
| Clinically-dosed adaptogens for cortisol | |||
| Zero added sugar — no glucose spike | |||
| Absorbed as a drink, not 6 capsules | |||
| Third-party tested batches | |||
| Formulated for women over 40 |
We'd rather tell you plainly than have you find out after three months.
Your cells stop responding properly to insulin, so your body makes more of it. High insulin drives fat storage around the middle, sugar cravings, energy crashes and higher testosterone — which is why the symptoms feel unrelated but aren't.
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